Based on this link: Edge redirecting to IE (at Reddit), there is apparently a way to show a special purpose page displaying:
This website needs Internet Explorer This website uses technology that will work best in Internet Explorer.
Open with Internet Explorer
Keep going in Microsoft Edge
It will be very helpful for my applications using Active X controls. I already have code such as:
<meta http-equiv="X-UA-Compatible" content="IE=10;requiresActiveX=true" />
in all my head sections (added in the past to avoid the Metro style for Windows 8), but it doesn't do the trick (unlike what someone mentioned in the link above).
One way of doing it is by including your site on the Enterprise Mode Site List so it will open in IE11 automatically:
The steps and the details can be found in this blog post by the Microsoft Edge team:
http://blogs.windows.com/msedgedev/2015/08/26/how-microsoft-edge-and-internet-explorer-11-on-windows-10-work-better-together-in-the-enterprise/