Mini Profiler does not render scripts

I've added Mini Profiler through NuGet and though in a really simple project works lovely, this is a big and existing project, and of course that I'm getting some problems with it :(

it writes the correct script tags in the source code as

<link rel="stylesheet" type="text/css" href="/mini-profiler-includes.css?v=1.9.0.0">
<script type="text/javascript">    
    if (!window.jQuery) document.write(unescape("%3Cscript src='/mini-profiler-jquery.1.6.2.js' type='text/javascript'%3E%3C/script%3E"));    
    if (!window.jQuery || !window.jQuery.tmpl) document.write(unescape("%3Cscript src='/mini-profiler-jquery.tmpl.beta1.js' type='text/javascript'%3E%3C/script%3E"));    
</script>    
<script type="text/javascript" src="/mini-profiler-includes.js?v=1.9.0.0"></script>    
<script type="text/javascript">    
    jQuery(function() {    
        MiniProfiler.init({    
            ids: ["e48fcf61-41b0-42e8-935a-fbb1965fc780","870a92db-89bc-4b28-a410-9064d6e578df","30881949-bfdb-4e3a-9ea5-6d4b73c28c1d","6bca31b8-69d9-48eb-b86e-032f4d75f646","df16838d-b569-47d0-93e6-259c03322394"],    
            path: '/',    
            version: '1.9.0.0',    
            renderPosition: 'left',    
            showTrivial: false,    
            showChildrenTime: false,    
            maxTracesToShow: 15    
        });    
    });    
</script>

But when I try to open any file, I get a HTTP 404

I verified that there is a MiniProfiler.cs under App_Start and adding a break point there, the code runs, I even added

#region Mini Profiler

protected void Application_BeginRequest()
{
    if (Request.IsLocal)
    {
        MiniProfiler.Start();
    }
}
protected void Application_EndRequest()
{
    MiniProfiler.Stop();
}

#endregion

to the global.asax file...

Is there something obviously that I'm missing?

This is a known issue with certain configurations of IIS.

The workaround is to ensure the UrlRoutingModule handles all the mini profiler includes in your web.config:

<system.webServer>
    <handlers>
        <add name="UrlRoutingModule1" path="mini-profiler*.js" verb="*" type="System.Web.Routing.UrlRoutingModule" resourceType="Unspecified" preCondition="integratedMode" />
        <add name="UrlRoutingModule2" path="mini-profiler*.css" verb="*" type="System.Web.Routing.UrlRoutingModule" resourceType="Unspecified" preCondition="integratedMode" />
        <add name="UrlRoutingModule3" path="mini-profiler*.tmpl" verb="*" type="System.Web.Routing.UrlRoutingModule" resourceType="Unspecified" preCondition="integratedMode" />
    </handlers>
</system.webServer>

There are 2 open tickets on this issue at the moment: