How to calculate p-values for pairwise correlation

2020-07-11 09:39发布

问题:

Pandas has the very handy function to do pairwise correlation of columns using pd.corr(). That means it is possible to compare correlations between columns of any length. For instance:

df = pd.DataFrame(np.random.randint(0,100,size=(100, 10)))

     0   1   2   3   4   5   6   7   8   9
0    9  17  55  32   7  97  61  47  48  46
1    8  83  87  56  17  96  81   8  87   0
2   60  29   8  68  56  63  81   5  24  52
3   42  76   6  75   7  59  19  17   3  63
...

Now it is possible to test correlation between all 10 columns with df.corr(method='pearson'):

      0         1         2         3         4         5         6         7         8         9
0  1.000000  0.082789 -0.094096 -0.086091  0.163091  0.013210  0.167204 -0.002514  0.097481  0.091020
1  0.082789  1.000000  0.027158 -0.080073  0.056364 -0.050978 -0.018428 -0.014099 -0.135125 -0.043797
2 -0.094096  0.027158  1.000000 -0.102975  0.101597 -0.036270  0.202929  0.085181  0.093723 -0.055824
3 -0.086091 -0.080073 -0.102975  1.000000 -0.149465  0.033130 -0.020929  0.183301 -0.003853 -0.062889
4  0.163091  0.056364  0.101597 -0.149465  1.000000 -0.007567 -0.017212 -0.086300  0.177247 -0.008612
5  0.013210 -0.050978 -0.036270  0.033130 -0.007567  1.000000 -0.080148 -0.080915 -0.004612  0.243713
6  0.167204 -0.018428  0.202929 -0.020929 -0.017212 -0.080148  1.000000  0.135348  0.070330  0.008170
7 -0.002514 -0.014099  0.085181  0.183301 -0.086300 -0.080915  0.135348  1.000000 -0.114413 -0.111642
8  0.097481 -0.135125  0.093723 -0.003853  0.177247 -0.004612  0.070330 -0.114413  1.000000 -0.153564
9  0.091020 -0.043797 -0.055824 -0.062889 -0.008612  0.243713  0.008170 -0.111642 -0.153564  1.000000

Is there a simple way to also get the corresponding p-values (ideally in pandas), as it is returned e.g. by scipy's kendalltau()?

回答1:

Probably just loop. It's basically what pandas does in the source code to generate the correlation matrix anyway:

import pandas as pd
import numpy as np
from scipy import stats

df_corr = pd.DataFrame() # Correlation matrix
df_p = pd.DataFrame()  # Matrix of p-values
for x in df.columns:
    for y in df.columns:
        corr = stats.pearsonr(df[x], df[y])
        df_corr.loc[x,y] = corr[0]
        df_p.loc[x,y] = corr[1]

If you want to leverage the fact that this is symmetric, so you only need to calculate this for roughly half of them, then do:

mat = df.values.T
K = len(df.columns)
correl = np.empty((K,K), dtype=float)
p_vals = np.empty((K,K), dtype=float)

for i, ac in enumerate(mat):
    for j, bc in enumerate(mat):
        if i > j:
            continue
        else:
            corr = stats.pearsonr(ac, bc)
            #corr = stats.kendalltau(ac, bc)

        correl[i,j] = corr[0]
        correl[j,i] = corr[0]
        p_vals[i,j] = corr[1]
        p_vals[j,i] = corr[1]

df_p = pd.DataFrame(p_vals)
df_corr = pd.DataFrame(correl)
#pd.concat([df_corr, df_p], keys=['corr', 'p_val'])


回答2:

why not using the "method" argument of pandas.DataFrame.corr():

  • pearson : standard correlation coefficient
  • kendall : Kendall Tau correlation coefficient
  • spearman : Spearman rank correlation
  • callable: callable with input two 1d ndarrays and returning a float from

scipy.stats import kendalltau, pearsonr, spearmanr

def kendall_pval(x,y):
    return kendalltau(x,y)[1]

def pearsonr_pval(x,y):
    return pearsonr(x,y)[1]

def spearmanr_pval(x,y):
    return spearmanr(x,y)[1]

and then

corr = df.corr(method=pearsonr_pval)


回答3:

This will work:

from scipy.stats import pearsonr

column_values = [column for column in df.columns.tolist() ]


df['Correlation_coefficent'], df['P-value'] = zip(*df.T.apply(lambda x: pearsonr(x[column_values ],x[column_values ])))
df_result = df[['Correlation_coefficent','P-value']]