How to test PH assumption with Schoenfeld residual

2019-08-16 02:43发布

问题:

I've obtained Schoenfeld residuals for testing PH for Fine & Gray's Cox regression model in presence of competing events with cmprsk.

Here's the code:

 fg<-crr( fu_m, event, diabetes,  failcode=1, cencode=0,
 na.action=na.omit, gtol=1e-06, maxiter=10, variance=TRUE)

fg$res
fg$uft
par(mfrow = c(1,1), mar = c(4.5,4,2,1))
for(j in 1:ncol(fg$res))
  fg$u
scatter.smooth(fg$uftime, fg$res[,j],
           main = names(fg$diabetes)[j],
           xlab = "Failure time",
           ylab = "Schoenfeld residuals")

Here's the output:

> fg$res
           [,1]
[1,]  0.5498603
[2,] -0.3957394
[3,] -0.4024953
[4,]  0.5905142
[5,] -0.3421397

> fg$uft
[1]  4.238193  6.275154 16.131417 27.498973 46.817248

Here's the plot:

I've done the same using SAS and I've obtained a p-value of 0,55 on 1000 simulated paths and this plot for observed path and first 20 simulated paths:

How can I check the PH assumption like I do with SAS? How can I introduce simulated paths?

Thank you all!!